• GM 6001

Ilomasta (GM 6001, Galardin^TM, N-[(2R)-2-(hydroxamidocarbonylmethyl)
-4-methylpentanoyl]-L-tryptophan methylamide) Board Spectruminhibitor of matrix metalloproteases (MMPs) with Kis in nM range. Widely used to
inhibit MMPs in vitro experiments and in animal models.
Reference:
Inhibits anthrax lethal factor with ki= 2.1 uM. B.E. Turk et al, Nature
Structural and Molecular Biology 11(1) January 2004, 60-65.
                                                    

• GM 1489

(N-[(2R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-
tryptophan (S)-methylbenzylamide) inhibitor of MMPs with specificity for
MMP1.Ki 0.2 Nm for MMP1≥Nm for other MMPs.

                                                    

• N-t-Butyloxycarbony1-L-lecucine-tryptophan methylamide.
  Negative control peptide for MMP inhibitor GM6001 AND GM 1489.

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